Zic2Controls Cerebellar Development in Cooperation withZic1
نویسندگان
چکیده
منابع مشابه
Zic2 controls cerebellar development in cooperation with Zic1.
Mouse Zic genes encode zinc finger proteins and are expressed in the developing and mature CNS. Reduced expression of Zic2 in mice results in spina bifida and holoprosencephaly. However, the disruption of Zic1, a strong homolog of Zic2 that has an overlapping expression pattern, results in cerebellar malformation with no apparent abnormalities in the forebrain or in posterior neuropore closure....
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2002
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.22-01-00218.2002